Theriappan P, Gupta AK, Dhasarathan P. 2011. Accumulation of Proline under Salinity and Heavy metal stress in Cauliflower seedlings. J  Appl Sci Environ Manag 15: 251–255.

Alia A, Saradhi P. 1991. Proline accumulation under heavy metal stress. J Plant Physiol 138: 554-558.

Apel K, Hirt H. 2004. Reactive oxygen species:Metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 55: 373-399.

Sayin S, Yilmaz AB, Ergün N, Turan1 F. 2011. Competitive biosorption of different forms of lead [Pb(NO3)2 and Pb(CH3COO)2] on growth, biomass and proline in Spirulina platensis (Cyanophyta). Afr J Biotechnol 10: 18458-18462.

Ataei-Azimi A, Hashemloian BD, Ebrahimzadeh H, Majd A. 2008. High in vitro production of ant-canceric indole alkaloids from periwinkle (Catharanthus roseus) tissue culture. Afr J Biotechnol 7: 2834-2839.

Bao T, Sun L, Xue H. 2011. Cadmium Accumulation and Antioxidative Defenses in Leaves of Zea mays L. Adv Mat Res 183: 99-103.

Bates L, Waldren R, Teare I. 1973. Rapid determination of free proline for water-stress studies. Plant Soil 39: 205-207.

Bidar G, Verdin A, Garçon G, Pruvot C, Laruelle F, Grandmougin-Ferjani A, Douay F, Shirali P. 2008. Changes in fatty acid composition and content of two plants (Lolium perenne and Trifolium repens) grown during 6 and 18 months in a metal (Pb, Cd, Zn) Contaminated Field. Water Air Soil Pollut 192: 281-291.

Cakmak I, Horst JH. 1991. Effects of aluminum on lipid peroxidation, superoxide dismutase, catalase, and peroxidase activities in root tips of soybean (Glycine max). Physiol Plantarum 83:463-468.

Enikeev A, Vysotskaya EF, Leonova LA, Gamburg KZ. 1995. Viability assay with 2,3,5-triphenyltetrazolium chloride in plant cell cultures. Russ J Plant Physiol 42: 372-375.

Fojtová M, Fulnečková J, Fajkus J, Kovařík A. 2002. Recovery of tobacco cells from cadmium stress is accompanied by DNA repair and increased telomerase activity. J Exp Biol 53: 2151-2158.

Giannopolitis CN, Ries SK. 1977. Superoxide Dismutases II. Purification and Quantitative Relationship with Water-soluble Protein in Seedlings. Plant Physiol Biochem 59: 315-318.

Kumar A, Patil D, Rajamohanan PR, Ahmad A. 2013. Isolation, purification and characterization of vinblastine and vincristine from endophytic fungus fusarium oxysporum isolated from Catharanthus roseus. PLoS One, 8: e71805. doi:10.1371/journal.pone.0071805.

Hisiger S, Jolicoeur M. 2007. Analysis of Catharanthus roseus alkaloids by HPLC. Phytochem Rev 6: 207-234.

Iakimova E, Woltering E, Kapchina-Toteva V, Harren F, Cristescu S. 2008. Cadmium toxicity in cultured tomato cells-role of ethylene, proteases and oxidative stress in cell death signaling. Cell Biol Int 32: 1521-1529.

Iannone MF, Rosales EP, Groppa MD, Benavides MP. 2013. H₂O₂ Involvement in Polyamine-induced cell death in tobacco leaf discs. J Plant Growth Regul 32: 745-757.

Israr M, Sahi SV, Jain J. 2006. Cadmium accumulation and antioxidative responses in the sesbania drummondii callus. Arch Environ Contam Toxicol 50: 121-127.

JinFen W, MingHua D, Ming G. 2012. Cd²⁺ stress induces two waves of H₂O₂ accumulation associated with ROS-generating system and ROS-scavenging system in cultured tobacco cells. Aust J Crop Sci 6: 846-853.

Keilig K, Ludwig-Muller J. 2009. Effect of flavonoids on heavy metal tolerance in Arabidopsis thaliana seedlings. Bot Stud 50: 311-318.

Kim S, Lim J, Park M, Kim Y, Park T, Seo YW, Choi KG, Yun SJ. 2005. Enhanced antioxidant enzymes are associated with reduced hydrogen peroxide in barley roots under saline stress. J Biochem Mol Biol 38: 218-224.

Lowry OH, Rosebrough NJ, Lewis Farr A, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.

Lee Y, Rubio MC, Alassimone J, Geldner N. 2013. A mechanism for localized lignin deposition in the endodermis. Cell 153: 402-412.

Livanos P, Apostolakos P, Galatis B. 2012. Plant cell division: ROS homeostasis is required. Plant Signal Behav 7: 771-778.

Ma W, Xu W, Xu H, Chen Y, He Z, Ma M. 2010. Nitric oxide modulates cadmium inXux during cadmium-induced programmed cell death in tobacco BY-2 cells. Planta 232: 325-335.

Marinova D, Ribarova F, Atanassova M. 2005. Total phenolics and total flavonoids in bulgarian fruits and vegetables. J Univ Chem Technol Metallurgy 40: 255-260.

Metwally A, Frnkemeier I, Georgi M, Dietz KJ. 2003. Salicylic acid alleviates the cadmium toxicity in barley seedlings. Plant Physiol Biochem 132:272-281.

Michalak A. 2006. Phenolic Compounds and Their Antioxidant Activity in Plants Growing, under Heavy Metal Stress. Polish J Environ Stud 15: 523-530.

Mittler R. 2002. Oxidative stress, antioxidants and stress tolerance. Trends Plant Sci 7: 405-410.

Mittova V, Volokita M, Guy M, Tal M. 2000. Activities of SOD and the ascorbate-glutathione cycle enzymes in subcellular compartments in leaves and roots of the cultivated tomato and its wild salt-tolerant relative Lycopersicon pennellii. Physiol Plantarum, 110: 45- 51.

Ohadoma S, Michael HU. 2011. Effects of co-administration of methanol leaf extract of Catharanthus roseus on the hypoglycemic activity of metformin and glibenclamide in rats. Asian Pac J Trop Med 4: 475-477.

Polle A, Otter T, Seifert F. 1994. Apoplastic peroxidases and lignification in needles of Norway spruce (Picea abies L.). Plant Physiol 106: 53-60.

Rucińiska-Sobkowiak R. 2010. Oxidative stress in plants exposed to heavy metals. Postepy Biochemii 56: 191-200.

Saifullah, Khan S. 2011. Callus induction and cell suspension culture production of catharanthus roseus for biotransfermation studies of (-)- caryophyllene oxide. Pak J Bot 43:  467-473.

Sergiv I, Karanov A. 1997. Effect of spermine, atrazine and combination between them on some endogenous protective systems and stress markers in plants. C R Acad Bulg Sci 51: 121-124.

Sharma P, Jha A, Dubey RS. 2010. Oxidative stress and antioxidative defense system in plants growing under abiotic Stresses. In: Pessarakli M, ed. Handbook of Plant and Crop Stress. Florida: CRC Press, 89–138.

Sharma P, Jha A, Dubey RS, PessarakliM. 2012. Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Bot 2012, Article ID 217037, 26 pages, 2012. doi:10.1155/2012/217037.

Singleton VL, Orthofer R, Lamuela-Raventos RM. 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol 299: 152-178.

Smeets K, Ruytinx J, Semane B, Belleghem F, Remans T, Sanden S, Vangronsvelda J, Cuypersa A. 2008. Cadmium-induced transcriptional and enzymatic alterations related to oxidative stress. Environ Exp Bot  63: 1-8.

Sreevidya N, Mehrotra S. 2003. Spectrophotometric method for estimation of alkaloids precipitable with Dragendorff's reagent in plant materials. J AOAC Int 86: 1124-1127.

Srivastava S, Tripathi R, Dwivedi UN. 2004. Synthesis of phytochelatins and modulation of antioxidants in response to cadmium stress in Cuscuta reflexa-an angiospermic parasite. J Plant Physiol 161: 665-674.

Wajda L, Kutemozinska W, Pilipowicz M. 1989. Cadmium toxicity to plant callus culture in vitro-I. Modulation by zinc a dependence on plant species and callus line. Environ Exp Bot  29: 301-305.

War A, Paulraj M, Ahmad T, Buhroo A, Hussain B, Ignacimuthu S. 2012. Mechanisms of plant defense against insect herbivores. Plant Signal Behav 7: 1306-1320.

Zheng Z, Wu M. 2004. Cadmium treatment enhances the production of alkaloid secondary metabolites in catharanthus roseus. Plant Sci 166: 507-514.