Abdifard E, Amin S, Bab S, Masroor N,. Khachian A, Heidari M. 2016. Incidence trends of colorectal cancer in Iran during 2000-2009: A population-based study. Med J Islam Repub Iran. 30: 382.

Aloia L, Di Stefano B, Di Croce L. 2013. Polycomb complexes in stem cells and embryonic development. Development 140: 2525-2534.

Barde I, Salmon P, Trono D. 2010. Production and titration of lentiviral vectors. In: Gerfen Ch, Holmes A, Sibley D, Skolnick Ph, Wray S, eds. Current Protocols in Neuroscience. New Jersey: John Wiley & Sons, 4.21.1-4.21.23.

Cai GH, Wang K, Miao Q, Peng YS, Chen XY.  2010. Expression of polycomb protein EZH2 in multi-stage tissues of gastric carcinogenesis. J Dig Dis 11: 88-93.

Cardoso C, Mignon G. Hetet B, Grandchamps B, Fontes M, Colleaux L. 2000. The human EZH2 gene: genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders. Eur J Hum Genet 8: 174-180.

Chou RH, Chiu L, Yu YL, Shyu WC. 2015. The potential roles of EZH2 in regenerative medicine. Cell Transplant 24: 313-317.

Damandan M, Moradpour Hesari R. 2016. The Association of pre-mir-196a2 T/C Polymorphism and Risk of Gastric Cancer in Ardabil, Iran. J Genet Resour 2: 48-51

Ferraro A, Boni T, Pintzas A. 2014. EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene. PLoS One 9: e115276.

Ferraro A, Mourtzoukou D, Kosmidou V, Avlonitis S, Kontogeorgos G, Zografos G, Pintzas A. 2013. EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells. Int J Biochem Cell Biol 45: 243-254.

Fussbroich B, Wagener N, Macher-Goeppinger S, Benner A, Falth M, Sultmann H, Holzer A, Hoppe-Seyler K, Hoppe-Seyler F. 2011. EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One 6: e21651.

He SB, Zhou H, Zhou J, Zhou GQ, Han T, Wan DW, Gu W, Gao L, Zhang Y, Xue XF, Zhang LF, Fei M, Hu SQ, Yang XD, Zhu XG, Wang L, Li DC. 2015. Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro. Exp Biol Med (Maywood) 240(4): 458-466.

Khosravi Shadmani F, Ayubi E, Khazaei S, Sani M, Mansouri Hanis S, Khazaei S, Soheylizad M, Mansori K. 2017. Geographic distribution of the incidence of colorectal cancer in Iran: a population-based study. Epidemiol Health 39: e2017020.

Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA, Chinnaiyan AM. 2003. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci USA 100: 11606-11611.

Mir Mohammadrezaei F. 2015. The Role of chk2 in Response to DNA Damage in Cancer Cells. J Genet Resour 1:31-34

Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D, Humphries RK, Griffith OL, Shah S, Zhu H, Kimbara M, Shashkin P, Charlot JF, Tcherpakov M, Corbett R, Tam A, Varhol R, Smailus D, Moksa M, Zhao Y, Delaney A, Qian H, Birol I, Schein J, Moore R, Holt R, Horsman DE, Connors JM, Jones S, Aparicio S, Hirst M, Gascoyne RD, Marra MA. 2010. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 42: 181-185.

O'Meara MM, Simon JA. 2012. Inner workings and regulatory inputs that control Polycomb repressive complex 2. Chromosoma 121: 221-234.

Porter AG, Janicke RU. 1999. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6: 99-104.

Society AC. 2014. Colorectal cancer facts and figures. Available at: https://www.cancer.org

Sun F, Chan E, Wu Z, Yang X, Marquez VE, Yu Q. 2009. Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. Mol Cancer Ther 8: 3191-3202.

Tan JZ, Yan Y, Wang XX, Jiang Y, Xu HE. 2014. EZH2: biology, disease, and structure-based drug discovery. Acta Pharmacol Sin 35: 161-174.

Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, Sanda MG, Ghosh D, Pienta KJ, Sewalt RG, Otte AP, Rubin MA, Chinnaiyan AM. 2002. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419: 624-629.

Xia H, Zhang W, Li Y, Guo N, Yu C. 2014. EZH2 silencing with RNA interference induces G2/M arrest in human lung cancer cells in vitro. Biomed Res Int 2014: 348728.

Yao Y, Hu H, Yang Y, Zhou G, Shang Z, Yang X, Sun K, Zhan S, Yu Z, Li P, Pan G, Sun L, Zhu X, He S. 2016. Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells. Genes (Basel): 7(10):83.

Zhang R, Wang R, Chang H, Wu F, Liu C, Deng D, Fan W. 2012. Downregulation of Ezh2 expression by RNA interference induces cell cycle arrest in the G0/G1 phase and apoptosis in U87 human glioma cells. Oncol Rep 28(6): 2278-2284.