تعداد نشریات | 31 |
تعداد شمارهها | 479 |
تعداد مقالات | 4,665 |
تعداد مشاهده مقاله | 7,304,066 |
تعداد دریافت فایل اصل مقاله | 5,466,250 |
اثر دو پروتکل تمرین تناوبی شدید بر مقادیر سرمی آیرزین بیماران مبتلا به دیابت نوع 2- کارآزمایی بالینی تصادفی | ||
پژوهشنامه فیزیولوژی ورزشی کاربردی | ||
دوره 19، شماره 38، اسفند 1402، صفحه 29-40 اصل مقاله (443.6 K) | ||
نوع مقاله: مقاله پژوهشی | ||
شناسه دیجیتال (DOI): 10.22080/jaep.2024.27097.2178 | ||
نویسندگان | ||
نوید وصال1؛ داریوش مفلحی2؛ سعید عابدین زاده* 3؛ حمید عباسی3؛ رضا شریفات پور3 | ||
1دانشجوی کارشناسی ارشد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه شهید باهنر کرمان، کرمان، ایران. | ||
2دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه شهید باهنر کرمان، کرمان، ایران. | ||
3استادیار گروه تربیت بدنی و علوم ورزشی، دانشکده روانشناسی و علوم تربیتی، دانشگاه یزد، یزد، ایران. | ||
تاریخ دریافت: 18 اردیبهشت 1403، تاریخ بازنگری: 27 خرداد 1403، تاریخ پذیرش: 12 تیر 1403 | ||
چکیده | ||
اهداف: هدف این پژوهش مقایسه تاثیر تمرینات اینتروال شدید (HIIT) با دو حجم بالا و پایین بر مقادیر سرمی آیرزین و شاخصهای آنتروپومتریکی مرتبط با سلامت در مردان مبتلا به دیابت نوع 2 بود. روش مطالعه: در این کارآزمایی بالینی تصادفی، 34 بیمار مرد مبتلا به دیابت نوع 2 به سه گروه ، تمرینات HIIT پرحجم، کمحجم و گروه کنترل دسته بندی شدند. هر دو پروتکل تمرینی HIIT شامل 24 جلسه بود که به مدت 8 هفته و هر هفته در 3 روز غیر متوالی اجرا شد. مقادیر سرمی آیریزین و شاخصهای آنتروپومتریکی (LBM, WHtR, WHR, BMI و درصد چربی) قبل و 48 ساعت بعد از جلسه پایانی تمرین اندازه گیری گردید. برای تحلیل و مقایسه داده ها از آزمون های آماری t همبسته، تحلیل کواریانس و آزمون تعقیبی LSD استفاده شده است. یافته ها: افزایش معنی داری بعد از 8 هفته تمرینات HIIT کم حجم و پر حجم در غلظت آیریزین سرمی مشاهده شد (05/0>p). هر دو نوع تمرین HIIT باعث کاهش معنیدار درصد چربی مردان مبتلا به دیابت نوع 2 شد (05/0>p). همچنین تمرینات HIIT پرحجم موجب کاهش شاخص آنتروپومتریکی WHtR شد (05/0>p). پس از تمرینات HIIT کم حجم کاهش معنادار شاخصهای آنتروپومتریکی BMI، WHtR و LBM مشاهده شد (05/0>p). نتیجه گیری: هر دو نوع تمرین HIIT کم حجم و پرحجم موجب بهبود سطوح سرمی آیریزین و شاخصهای آنتروپومتریکی بیماران مبتلا به دیابت نوع 2 میشود. بنابراین با توجه به صرفه زمانی، هر دو نوع تمرین HIITجهت بهبود شرایط بیماران مبتلا به دیابت نوع 2 توصیه میشود. | ||
کلیدواژهها | ||
آیریزین؛ دیابت نوع 2؛ HIIT؛ شاخصهای آنتروپومتریکی؛ درصد چربی بدن | ||
عنوان مقاله [English] | ||
The Effect of Two High-Intensity Interval Training Protocols on Serum Irisin Levels in Patients with Type 2 Diabetes - A Randomized Clinical Trial | ||
نویسندگان [English] | ||
Navid Vesal1؛ Dariush Moflehi2؛ Saeed Abedinzadeh3؛ Hamid Abbasi3؛ Reza Sharifatpour3 | ||
1Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Shahid Bahonar University of kerman, Kerman, Iran. | ||
2Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Shahid Bahonar University of kerman, Kerman, Iran. | ||
3Department of Sports Sciences, Faculty of Psychology and Educational Sciences, Yazd University, Yazd, Iran. | ||
چکیده [English] | ||
Objectives: The aim of this study was to investigate the effects of high and low-volume high-intensity interval training (HIIT) on serum irisin levels and health-related anthropometric indices in men with type 2 diabetes. Methods: In this randomized clinical trial, 34 male patients with type 2 diabetes were divided into three groups: high-volume HIIT, low-volume HIIT, and control. Both HIIT training protocols consisted of 24 sessions, performed on 3 non-consecutive days each week for 8 weeks. Serum irisin levels and anthropometric indices (LBM, WHtR, WHR, BMI and body fat percentage) were measured before and 48 hours after the final exercise session. Paired t-tests, analysis of covariance and LSD post hoc tests were used to analyze and compare the data. Results: A significant increase was observed in serum irisin concentrations after 8 weeks of low-volume and high-volume HIIT exercises (p<0.05). Both types of HIIT training significantly reduced the percentage of fat in men with type 2 diabetes (p<0.05). High-volume HIIT training also reduced the anthropometric index WHtR (p<0.05). After low-volume HIIT training, a significant decrease in the anthropometric indices BMI, WHtR and LBM was observed (p<0.05). Conclusion: Both types of low-volume and high-volume HIIT training improve serum irisin levels and anthropometric indices in patients with type 2 diabetes. Therefore, considering the time savings, both types of HIIT training are recommended to improve the conditions of patients with type 2 diabetes. | ||
کلیدواژهها [English] | ||
Irisin, Type 2 Diabetes, HIIT, Anthropometric Indices, Body Fat Percentage | ||
مراجع | ||
##Ahmed, T. M., Nassar, M., Mohamed, H. A. A., Elhadidy, K. E. s., Farhan, H. M., El Basset, A. S. A., Elmessiery, R. M., & Kamel, M. F. (2023). Evaluation of serum levels of Irisin as a marker of endothelial dysfunction in patients with type 2 diabetes mellitus. Endocrinology, Diabetes & Metabolism, 6(3), e403. ##Alizadeh, L., & Tofighi, A., & Tolouei Azar, J. (2019). The Effect of 8 Weeks of High Intensity Interval Training (HIIT) On Serum Irisin, FGF21 and Glycemic Indices in Type 2 Diabetic Women. Journal of Applied Health Studies in Sport Physiology, 6(2), 17-24. ##Arrieta-Leandro, M., Moncada-Jiménez, J., Morales-Scholz, M., & Hernández-Elizondo, J. (2023). The effect of chronic high-intensity interval training programs on glycaemic control, aerobic resistance, and body composition in type 2 diabetic patients: a meta-analysis. Journal of Endocrinological Investigation, 46(12), 2423-2443. ##Bahram, M. E., & Mogharnasi, M. (2015). The effect of twelve weeks high intensity training interval (HIIT) on leptin levels and obesity dependent factors among female students suffering overweight. Journal of Sport Biosciences, 6(4), 451-465. ##Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., & Long, J. Z. (2012). A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature, 481(7382), 463-468. ##Delfan, M., Saeidi, A., Supriya, R., Escobar, K. A., Laher, I., Heinrich, K. M., Weiss, K., Knechtle, B., & Zouhal, H. (2024). Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males. Nutrition & Metabolism, 21(1), 11. ##Gharari Arefi, R., Hemati Nafar, M., & Kordi, M. R. (2014). The effect of a high intensity interval training program on lipid profile in sedentary young men. Journal of Sport Biosciences, 6(3), 259-272. ## Golshan, H., Toloee, M. E., Abbasi, H., & Namiranian, N. (2020). Effect of different HIIT protocols on the glycemic control and lipids profile in men with type 2 diabetes: a randomize control trial. Iranian journal of diabetes and obesity. ##Gulati, M., Pandey, D. K., Arnsdorf, M. F., Lauderdale, D. S., Thisted, R. A., Wicklund, R. H., Al-Hani, A. J., & Black, H. R. (2003). Exercise capacity and the risk of death in women: the St James Women Take Heart Project. Circulation, 108(13), 1554-1559. ##Khammassi, M., Ouerghi, N., Hadj-Taieb, S., Feki, M., Thivel, D., & Bouassida, A. (2018). Impact of a 12-week high-intensity interval training without caloric restriction on body composition and lipid profile in sedentary healthy overweight/obese youth. Journal of exercise rehabilitation, 14(1), 118. ## Liu, J.-x., Zhu, L., Li, P.-j., Li, N., & Xu, Y.-b. (2019). Effectiveness of high-intensity interval training on glycemic control and cardiorespiratory fitness in patients with type 2 diabetes: a systematic review and meta-analysis. Aging clinical and experimental research, 31, 575-593. ## Liu, R., Lyu, L., Wu, Y., & Wang, L. (2024). Effects of high-intensity interval training and moderate-intensity continuous training on body composition and glucose metabolism in overweight or obese patients with type 2 diabetes: a Meta-analysis. Chinese Journal of Tissue Engineering Research, 28(14), 2274. ##Malekinezhad, H., Moflehi, D., Abbasi, H., & Behzadi, A. (2019). Effect of the Low or High Volume of High-Intensity Interval Training Protocols on the Leptin and Lipid Profile in Men with Type 2 Diabetes. Journal of Community Health Research. ##Mohammadi, B., & Tofighi, A. (2016). The effect of 8 weeks high intensity interval training on plasma irisin and subcutaneous adipose tissue UCP-1in male obese rats. ##Niyazi, A., Yasrebi, S. M. A., Yazdanian, M., & Mohammad Rahimi, G. R. (2024). High-Intensity Interval Versus Moderate-Intensity Continuous Exercise Training on Glycemic Control, Beta Cell Function, and Aerobic Fitness in Women with Type 2 Diabetes. Biological Research For Nursing, 26(3), 449-459. ##Racil, G., Coquart, J., Elmontassar, W., Haddad, M., Goebel, R., Chaouachi, A., Amri, M., & Chamari, K. (2016). Greater effects of high-compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biology of sport, 33(2), 145-152. ##Rezaei Manesh, D. (2024). Responses of plasma levels of irisin, follistatin and insulin resistance index to two types of high-intensity interval training in overweight men. Journal of Sport & Exercise Physiology (JSEP)/Fīziyuluzhī-i Varzish va Fa̒āliyyat-i Badanī, 16(4). ## Riahy, S. (2024). The effects of 12 weeks of high-intensity interval training and moderate-intensity continuous training on FGF21, irisin, and myostatin in men with type 2 diabetes mellitus. Growth Factors, 42(1), 24-35. ##Shirvani, H., & Aslani, J. (2017). The effects of high-intensity interval training vs. moderate-intensity continuous training on serum irisin and expression of skeletal muscle PGC-1α gene in male rats. Tehran University Medical Journal, 75(7), 513-520. ##Soori, R., Asad, M. R., Khosravi, M., & Abbasian, S. (2016). Comparison of the effects of regular aerobic training irisin serum changes in sedentary obese men. Iranian Journal of Endocrinology and Metabolism, 18(4), 270-278. ##Souri, R., Khosravi, N., Yazdan Dost, H., & Hossein Aiti, M. (2016). A comparison of moderate intensity continuous training and high intensity interval training on serum levels of Resistin and Insulin resistance in type-2 diabetic obese women. Journal of Sport Biosciences, 8(3), 365-380. ##Tofighi, A., Alizadeh, R., & Tolouei Azar, J. (2017). The effect of eight weeks high intensity interval training (HIIT) on serum amounts of FGF21 and irisin in sedentary obese women. Studies in Medical Sciences, 28(7), 453-466. ##Trapp, E. G., Chisholm, D. J., Freund, J., & Boutcher, S. H. (2008). The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. International journal of obesity, 32(4), 684-691. ## Vahdat, H., Mombini, H., Eslami Farsani, M., Ab Abzadeh, S., & Barzegar, H. (2018). Effect of High-Intensity Interval Training (HIIT) on the levels of Irisin and interleukin-10 in overweight men. Qom University of Medical Sciences Journal, 12(2), 35-44. ##Vecchiato, M., Zanardo, E., Battista, F., Quinto, G., Bergia, C., Palermi, S., Duregon, F., Ermolao, A., & Neunhaeuserer, D. (2022). The effect of exercise training on irisin secretion in patients with type 2 diabetes: a systematic review. Journal of clinical medicine, 12(1), 62. ##Winding, K. M., Munch, G. W., Iepsen, U. W., Van Hall, G., Pedersen, B. K., & Mortensen, S. P. (2018). The effect on glycaemic control of low‐volume high‐intensity interval training versus endurance training in individuals with type 2 diabetes. Diabetes, Obesity and Metabolism, 20(5), 1131-1139. ## Wrann, C. D., White, J. P., Salogiannnis, J., Laznik-Bogoslavski, D., Wu, J., Ma, D., Lin, J. D., Greenberg, M. E., & Spiegelman, B. M. (2013). Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell metabolism, 18(5), 649-659. ## | ||
آمار تعداد مشاهده مقاله: 164 تعداد دریافت فایل اصل مقاله: 32 |